MABT63

Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4

clone N3.12.4, from mouse

• Sinônimo(s): poliovirus receptor-related 3, poliovirus receptor-related protein 3, nectin 3, nectin-3, Nectin-3, CD113 antigen
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: N3.12.4, monoclonal
• reatividade de espécies: human
• técnica(s): flow cytometry: suitable
• Isotipo: IgG2aκ
• nº de adesão NCBI: NP_056295
• nº de adesão UniProt: Q9NQS3
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... NECTIN3(25945)

Descrição

Descrição geral

Nectin-3, also known as Poliovirus receptor-related protein 3 (PVRL3) and PRR3, is thought to work with cadherin to form cell-cell adherens junctions. It is a transmembrane protein that is commonly found in the testis and in placental tissue. Nectin-3 colocalizes with CD155, the cognate receptor for poliovirus, to cell-cell junctions. Nectin-3′s involvement in down-regulation PVR from the cell surface leads to a reduction in cell motility and proliferation.

Imunogênio

Full length recombinant protein corresponding to human Nectin-3.

Aplicação

Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4 detects level of Nectin-3/PVRL3 (CD113) & has been published & validated for use in FC.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Qualidade

Evaluated by Flow Cytometry in U251 cells.

Flow Cytometry Analysis: 0.1 µg of this antibody detected Nectin-3 in U251 cells.

Descrição-alvo

61 kDa calculated

forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
U251 cells

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable