MABE162

Anti-IGHMBP2 Antibody, clone11-24

clone mAb11-24, from mouse

• Sinônimo(s): immunoglobulin mu binding protein 2, DNA-binding protein SMUBP-2, cardiac transcription factor 1, Immunoglobulin mu-binding protein 2, Glial factor 1, ATP-dependent helicase IGHMBP2
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: mAb11-24, monoclonal
• reatividade de espécies: human
• técnica(s): immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotipo: IgG2bκ
• nº de adesão NCBI: NP_002171
• nº de adesão UniProt: P38935
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... IGHMBP2(3508)

Descrição

Descrição geral

Immunoglobulin mu-binding protein 2 (IGHMBP2) is a nucleic acid binding protein that acts on both RNA and DNA. The mature protein contains an ATP-dependent RNA/DNA helicase domain, an R3H single-stranded nucleic acid-binding domain, and a zinc finger domain. Consistent with these multiple functional domains, in vitro data suggests this protein is involved in and array of cellular functions such as transcriptional activation, DNA replications immunoglobulin class switching, pre-mRNA splicing, and translation.

Imunogênio

Recombinant Protein corresponding to human IGHMBP2.

Aplicação

Anti-IGHMBP2 Antibody, clone11-24 is a Mouse Monoclonal Antibody for detection of IGHMBP2 also known as immunoglobulin mu binding protein 2, DNA-binding protein SMUBP-2 & has been validated in WB, ICC & IP.

Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (de Planell-Saguer, M., et al. (2009). Hum Mol Genet. 18(12):2115-2126.)

Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP. (de Planell-Saguer, M., et al. (2009). Hum Mol Genet. 18(12):2115-2126.)

Qualidade

Evaluated by Western Blot in Hek293 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected IGHMBP2 on 10 µg of Hek293 cell lysate.

Descrição-alvo

~110 kDa observed. Band observed at ~60 kDa may be a proteolytic fragment of IGHMBP2. (de Planell-Saguer, M., et al. (2009). Hum Mol Genet. 18(12):2115-2126.)

forma física

Format: Purified

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable