This product is carrier-free and does not contain glycerol, gelatin, or serum albumin. The antibody has not been tested for the suitability in Hyperion imaging application. The end-user will have to determine the suitability.
MABC539
Anti-SFRP2 Antibody, clone 80.8.6, azide free
clone 80.8.6, from mouse
Sinônimo(s):
Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
forma do anticorpo
purified antibody
tipo de produto de anticorpo
primary antibodies
clone
80.8.6, monoclonal
reatividade de espécies
human
técnica(s)
immunohistochemistry: suitable
inhibition assay: suitable
Isotipo
IgG2aκ
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... SFRP2(6423)
Categorias relacionadas
Descrição geral
Secreted frizzled-related proteins (SFRPs) may play a critical role in carcinogenesis by inhibiting the Wnt/beta-catenin signaling pathway. Secreted frizzled-related protein 2 (SFRP2) may be useful to further investigate mammary tumorigenesis as its expression increases with tumor progression in canine mammary gland tumors. SFRP2 in mouse embryos has been found to cause severe shortening of the thoracic region. Studies have shown that this protein is the essential stem cell paracrine factor that is thought to regulate myocardial survival and repair damage in the aftermath of an ischemic injury.
Imunogênio
Epitope: NTR domain
Linear peptide corresponding to the NTR domain of human SFRP2.
Aplicação
Anti-SFRP2 Antibody, clone 80.8.6, azide free is an antibody against SFRP2 for use in IHC & inhibition.
Inhibition Assay Analysis: Anti-SFRP2, clone 80.8.6 inhibits tube formation and cell migration in vitro on SVR angiosarcoma cells, inhibits angiosarcoma and breast cancer growth in vivo, and increases nuclear NFATc3 levels.
Qualidade
Evaluated by Immunohistochemistry in human prostate and human breast cancer tissue.
Imunnohistochemistry Analysis: A 1:500 dilution of this antibody detected SFRP2 in human prostate and human breast cancer tissue.
Imunnohistochemistry Analysis: A 1:500 dilution of this antibody detected SFRP2 in human prostate and human breast cancer tissue.
Descrição-alvo
33 kDa calculated
forma física
Format: Purified
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Our department is interested in your anti-SFRP antibody (MABC539). We would like to use it for Hyperion imaging. Hence, the antibody has to be glycerol free, BSA free, gelatine free, carrier free and unconjugated. Is the antibody presented in 100% PBS?
1 answer-
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