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Merck
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Documentos Principais

MAB1581

Sigma-Aldrich

Anti-Aggrecan Antibody

CHEMICON®, mouse monoclonal, Cat-315

Sinônimo(s):

CSPG

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.

Nome do produto

Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315, ascites fluid, clone Cat-315, Chemicon®

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

ascites fluid

tipo de produto de anticorpo

primary antibodies

clone

Cat-315, monoclonal

reatividade de espécies

feline, rat

fabricante/nome comercial

Chemicon®

técnica(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgM

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... ACAN(176)

Especificidade

Chondroitin sulfate proteoglycan (CSPG), protein core epitope

Imunogênio

Epitope: Core Protein Epitope

Aplicação

Immunohistochemistry: 1:2,000 on 4% paraformaldehyde fixed frozen tissue.

Immunocytochemistry: 1:500 on primary cultures of neurons.

Immunoblot: 1:5,000 recognizes a band at 680 kDa.

Immunoprecipitation.

Optimal working dilutions must be determined by the end user.
This Anti-Chondroitin Sulfate Proteoglycan Antibody, Core Protein Epitope, clone Cat-315 is validated for use in IP, WB, IC, IH for the detection of Chondroitin Sulfate Proteoglycan.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Andrew Nathaniel Stewart et al.
Restorative neurology and neuroscience, 35(4), 395-411 (2017-06-10)
Utilizing genetic overexpression of trophic molecules in cell populations has been a promising strategy to develop cell replacement therapies for spinal cord injury (SCI). Over-expressing the chemokine, stromal derived factor-1 (SDF-1α), which has chemotactic effects on many cells of the
Claudia Loebel et al.
Advanced functional materials, 30(44) (2021-07-03)
Hydrogels are engineered with biochemical and biophysical signals to recreate aspects of the native microenvironment and to control cellular functions such as differentiation and matrix deposition. This deposited matrix accumulates within the pericellular space and likely affects the interactions between
Paulette A McRae et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(20), 5405-5413 (2007-05-18)
An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent studies. However, identification of the critical molecular components of the neural matrix that mediate these processes is far
Alicia L Hawthorne et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(2), 420-430 (2010-01-15)
Embryonic CNS neurons can migrate from the ventricular zone to their final destination by radial glial-guided locomotion. Another less appreciated mechanism is somal translocation, where the young neuron maintains its primitive ventricular and pial processes, through which the cell body
Shinji Miyata et al.
Frontiers in integrative neuroscience, 12, 3-3 (2018-02-20)
Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain development. Emerging evidence indicates that PNNs promote the maturation of PV cells

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