ABS521

Anti-RSK4 Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): Q9UK32, KS6A6_HUMAN, RPS6KA6, RSK4, Q9UK32, B2R854, Q6FHX2, Q8WX28, Q9H4S6, Ribosomal protein S6 kinase alpha-6, p90RSK6
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: rat
• reatividade da espécie (prevista por homologia): human (based on 100% sequence homology), bovine (based on 100% sequence homology)
• técnica(s): immunoprecipitation (IP): suitable; western blot: suitable
• nº de adesão NCBI: NP_055311
• nº de adesão UniProt: Q9UK32
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... RPS6KA6(27330)

Descrição

Descrição geral

RSK1, RSK2, RSK3, and RSK4 (ribosomal protein S6 kinase, 90 kDa, polypeptide 1,2,3, and 4; S6K-alpha 1,2,3, and 4) are Ser/Thr kinases which are activated by MAP Kinases. Ribosomal S6-kinase 4 (RSK4) is thought to be mapped in the critical region that is commonly deleted in X-linked deafness type 3, mental retardation, and choroideremia. It may be involved in normal neuronal development. RSK4 is also thought to play a role in non-growth factor signaling and may also be important in tumor suppression.

Imunogênio

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of Human RSK4.

Aplicação

Immunoprecipitation analysis: 10 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.5 mg PC12 or EGF treated PC12 cell lysate
Immunoprecipitation analysis: 5 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.665mg of PC12 cell lysate. Uncharacterized bands may be detected at high antibody concentration or longer exposures

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

General Post-translation Modification

This Anti-RSK4 Antibody is validated for use in Western Blotting and Immunoprecipitation for the detection of RSK4.

Qualidade

Evaluated by Western Blotting in rat PC12 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RSK4 in 10 µg of rat PC12 cell lysate.

Descrição-alvo

~83 kDa observed. Uncharacterized band(s) may appear in some lysates.

Ligação

Replaces: 04-1132

forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to lot specific datasheet.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable