ABS448

Anti-CSN8 Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): CSN8 Antibody, COP9 signalosome complex subunit 8, SGN8, JAB1-containing signalosome subunit 8, CSN8
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: human
• técnica(s): western blot: suitable
• nº de adesão UniProt: Q99627
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... COPS8(10920)

Descrição

Descrição geral

COP9 signalosome complex subunit 8 (CSN8, COPS8), also known as Signalosome subunit 8 (SGN8), is a nuclear-enriched protein complex belonging to the CSN8 family. It is comprised of eight subunits that interact with deubiquitinating enzymes and protein kinases. The CSN complex is involved in the regulation of various signaling and developmental processes, including DNA repair, cell cycle regulation, embryogenesis, axonal guidance, MAPK cascade, immune response, and hormonal signaling.

Especificidade

This antibody recognizes the C-terminus of CSN8.

Imunogênio

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human CSN8.

Aplicação

Anti-CSN8 Antibody is a highly specific rabbit polyclonal antibody, that targets COP9 signalosome complex subunit 8 & has been tested in western blotting.

Research Category
Signaling

Research Sub Category
Developmental Signaling

Qualidade

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CSN8 in 15 µg of human liver tissue lysate.

Descrição-alvo

~27 and ~30 kDa observed. Uniprot describes 2 isoforms at ~18 kDa and ~23 kDa Uncharacterized bands may appear in some lysate(s).

Ligação

Replaces: MABN1028

forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Human liver tissue lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable