ABC832

Anti-TMEM16B Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): Anoctamin-2, Transmembrane protein 16B
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: human, rat
• técnica(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• nº de adesão UniProt: Q9NQ90
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... ANO2(57101)

Descrição

Descrição geral

Anoctamin-2, also known as Transmembrane protein 16B (TMEM16B) are subunits of Calcium-activated chloride channels (CaCC) which mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC’s but has different biophysical characteristics such as voltage dependence and unitary conductance.

Especificidade

This antibody will not cross-react with TMEM16A.

Imunogênio

Epitope: N-terminus

KLH-conjugated synthetic peptide corresponding to the N-terminus of human TMEM16B.

Aplicação

Anti-TMEM16B Antibody is an antibody against TMEM16B for use in western blotting, IHC & immunofluorescence.

Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected TMEM16B in human brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TMEM16B in human brain cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualidade

Evaluated by Western Blotting in rat brain tissue.

Western Blotting Analysis: 2 μg/mL of this antibody detected TMEM16B in rat brain tissue.

Descrição-alvo

~128 kDa observed. Uncharacterized bands may be observed in some lysate(s).

forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable