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Merck
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AB9042

Sigma-Aldrich

Anti-Brain Derived Neurotrophic Factor Antibody, pro

Chemicon®, from chicken

Sinônimo(s):

proBDNF, pro BDNF

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

chicken

Nível de qualidade

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

mouse, rat, human

fabricante/nome comercial

Chemicon®

técnica(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... BDNF(627)

Especificidade

Reacts with proBDNF. Does not recognize mature BDNF isoforms.

Imunogênio

Fusion protein from mouse proBDNF containing only the prodomain region.

Aplicação

Anti-Brain Derived Neurotrophic Factor Antibody, pro detects level of Brain Derived Neurotrophic Factor & has been published & validated for use in IP, WB, IH.
Western blot: 1:500-1:1,000. Reacts with bands of 30 kD and 28 kD.Immunohistochemistry: 1:100-1:250 on frozen sections.

Immunohistochemistry: 1:100-1:200

Immunoprecipitation: 1:100

Optimal working dilutions must be determined by the end user.

forma física

Chicken immunoglobulin. Liquid.
Format: Semi-Purified

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Alta Berger et al.
Endocrinology, 157(2), 600-610 (2015-12-17)
In both mice and patients with Albright hereditary osteodystrophy, heterozygous inactivating mutations of Gsα, a ubiquitously expressed G protein that mediates receptor-stimulated intracellular cAMP production, lead to obesity and insulin resistance but only when the mutation is present on the
Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice.
Papaleo, F; Silverman, JL; Aney, J; Tian, Q; Barkan, CL; Chadman, KK; Crawley, JN
Learning & Memory null
Heejung Chun et al.
Experimental neurobiology, 27(3), 155-170 (2018-07-20)
Astrocytes are the most abundant cell type in the brain and they make close contacts with neurons and blood vessels. They respond dynamically to various environmental stimuli and change their morphological and functional properties. Both physiological and pathological stimuli can
Matteo Bergami et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(28), 11464-11478 (2013-07-12)
In the adult rodent brain, the olfactory bulb (OB) is continuously supplied with new neurons which survival critically depends on their successful integration into pre-existing networks. Yet, the extracellular signals that determine the selection which neurons will be ultimately incorporated
Beatrice Vignoli et al.
Communications biology, 4(1), 1152-1152 (2021-10-07)
Memory consolidation requires astrocytic microdomains for protein recycling; but whether this lays a mechanistic foundation for long-term information storage remains enigmatic. Here we demonstrate that persistent synaptic strengthening invited astrocytic microdomains to convert initially internalized (pro)-brain-derived neurotrophic factor (proBDNF) into

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