8.21111

2-Thiazoline-2-thiol

for synthesis

• Sinônimo(s): 2-Thiazoline-2-thiol, 2-Mercaptothiazoline
• Fórmula empírica (Notação de Hill): C₃H₅NS₂
• Número CAS: 96-53-7
• Peso molecular: 119.21
• Número MDL: MFCD00126013
• Código UNSPSC: 12352113
• Número do índice EC: 202-512-1
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Formulário: powder
• potência: 300 mg/kg LD₅₀, oral (Rat)
• pH: 6-7 (20 °C, 10 g/L in H₂O)
• pf: 101-106 °C
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: S1CCNC1=S
• InChI: 1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
• chave InChI: WGJCBBASTRWVJL-UHFFFAOYSA-N

Descrição

Aplicação

• Inducing apoptosis in melanoma cells: A study described a ruthenium(II) complex with 2-mercaptothiazoline ligand inducing selective cytotoxicity by causing DNA damage and apoptosis specifically in melanoma cells, highlighting its potential as a therapeutic agent in oncology (de Melo et al., 2024).
• Antimicrobial and synergistic activities: Thiazoline derivatives, including compounds related to 2-mercaptothiazoline, were studied for their antimicrobial and synergistic effects with conventional antibiotics against multidrug-resistant Staphylococcus aureus, presenting a potential strategy for enhancing antibiotic efficacy (Khan et al., 2020).
• Antimicrobial investigation of metal complexes: The antimicrobial properties of Cd(II) and Sn(II) complexes with 2-mercaptothiazoline were evaluated, underscoring the compound′s role in enhancing the bioactivity of metal-based therapeutics (Gaber et al., 2021).

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301
• Declarações de precaução: P264 - P270 - P301 + P310 - P405 - P501
• Classificações de perigo: Acute Tox. 3 Oral
• Código de classe de armazenamento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable