581004

Telomerase Inhibitor III, Sodium Salt

The Telomerase Inhibitor III, Sodium Salt controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

• Sinônimo(s): TAG-6, 5ʹ-d(TTAGGG)-3ʹ
• Código UNSPSC: 12352200

Propriedades

• Nível de qualidade: 100
• Formulário: lyophilized
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; desiccated (hygroscopic); protect from light
• solubilidade: water: soluble
• Condições de expedição: wet ice
• temperatura de armazenamento: −70°C

Descrição

Descrição geral

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomer mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM.

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomere mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM. Note: 150 nmol = 285 µg.

M.W. ~1900.

Ações bioquímicas/fisiológicas

Cell permeable: yes

Primary Target
Telomerase activity in cell lysates

Product competes with ATP.

Reversible: no

Embalagem

Packaged under inert gas

Advertência

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Sequência

5′-d(TTAGGG)-3′

Outras notas

Mata, J.E., et al. 1997. Toxicol. Appl. Pharmacol. 144, 189.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable