345744

Ganglioside GT_1b, Trisialo, Triammonium Salt, Bovine Brain

Inhibits Con A-stimulated mitogenesis in murine T cells.

• Sinônimo(s): Ganglioside GT_1b, Trisialo, Triammonium Salt, Bovine Brain, Neu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
• Fórmula empírica (Notação de Hill): C₉₅H₁₆₂N₅O₄₇ · 3NH₄
• Peso molecular: 2180.42
• Código UNSPSC: 12352211
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (TLC)
• Formulário: lyophilized
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• solubilidade: ethanol: soluble; methanol: soluble
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Inhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD_1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.

M.W. 2180.5 (based on stearoyl - 18:0).

Trisialoganglioside prepared from bovine gray matter. Readily converted to GD_1b-disialoganglioside by bacterial and mammalian sialidases without detergent or bile salts. Inhibits mitogenesis in concanavalin A-stimulated murine T-cells. Lymphocyte marker in cancer patients.



Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.

Ações bioquímicas/fisiológicas

Cell permeable: no

Primary Target
Inhibits Con A-stimulated mitogenesis in murine T cells

Product does not compete with ATP.

Reversible: no

Advertência

Toxicity: Irritant (B)

Nota de preparo

For use in aqueous systems, dissolve in a small amount of ethanol and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions can be filter sterilized.

Reconstituição

Following reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.

Outras notas

Hakomori, S. 1985. Cancer Res.45, 2405.
Momoi, T., et al. 1976. Biochim. Biophys. Acta441, 488.
Warren, L. 1959. J. Biol. Chem.234, 1971.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable