14-923-M
Flt1 Protein, active, 10 µg
Active, N-terminal GST-tagged, recombinant, human Flt1, amino acids 783-end. For use in Kinase Assays.
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About This Item
Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32
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Descrição geral
Product Source: N-terminal GST-tagged, recombinant, human Flt1 amino acids 783-end, expressed by baculovirus in Sf21 insect cells.
This protein encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Aplicação
Research Category
Signaling
Signaling
Ações bioquímicas/fisiológicas
Protein Target: Flt1
Target Sub-Family: TK
Embalagem
Also available in 250μg size as catalog # 14-923M and in bulk as catalog # 14-923-K.
Qualidade
Routinely evaluated by phosphorylation of peptide KKKSPGEYVNIEFG
forma física
50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Purified using glutathione sepharose.
Armazenamento e estabilidade
6 months at -70°C
Outras notas
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Informações legais
GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Skin Sens. 1
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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