14-818-M

Met (D1246N) Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N, for use in Kinase Assays.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Propriedades

• fonte biológica: human
• Nível de qualidade: 300
• recombinante: expressed in Sf21 cells
• peso molecular: M_w 50.1 kDa
• fabricante/nome comercial: Upstate^®
• técnica(s): activity assay: suitable (kinase)
• nº de adesão UniProt: J02958; P08581

Descrição

Descrição geral

Met D1246N is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.

N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N

Product Source: expressed by baculovirus in Sf21 insect cells

Ações bioquímicas/fisiológicas

Protein Target: Met

Target Sub-Family: TK

Embalagem

Available in 250 μg --call for pricing and availability and reference catalog number 14-818M when ordering the 250 μg size.

forma física

Ni²⁺/NTA-agarose

Armazenamento e estabilidade

6 months at -70°C

Outras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable