14-700

NEK11 Protein, active, 10 µg

• Código UNSPSC: 12352202
• eCl@ss: 32160405

Propriedades

• recombinante: expressed in baculovirus infected Sf21 cells
• Nível de qualidade: 100
• descrição: protein target NEK11
• purificado por: (Ni²⁺/NTA-agarose)
• técnica(s): activity assay: suitable
• nº de adesão UniProt: Q8NG66
• Informações sobre genes: human ... NEK11(79858)

Descrição

Descrição geral

FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.

Qualidade

routinely evaluated by phosphorylation of MBP (Catalog # 13-104)

propriedades físicas

59.3kDa

Armazenamento e estabilidade

6 months at -70°C from date of shipment

Nota de análise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable