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Merck
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Documentos

12-241

Sigma-Aldrich

Phospho-Glycogen Synthase Peptide-2

lyophilized, for Kinase Assays

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About This Item

Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.41

product name

Phospho-Glycogen Synthase Peptide-2, Phospho-Glycogen Synthase Peptide-2 primarily used in Kinase Assays.

Nível de qualidade

forma

lyophilized

fabricante/nome comercial

Upstate®

técnica(s)

activity assay: suitable (kinase)

Condições de expedição

wet ice

Categorias relacionadas

Qualidade

Routinely evaluated as a substrate of active GSK3β (Catalog # 14-306) to catalyze the incorporation of phosphate into phospho-glycogen synthase peptide-2.

Armazenamento e estabilidade

Lyophilized: Stable for 2 years at -20°C from date of shipment. Rehydrated: Stable for 6 months at -20°C. Aliquot rehydrated solution to avoid repeated freezing and thawing.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Use of peptide substrates for affinity purification of protein-serine kinases.
Woodgett, J R
Analytical biochemistry, 180, 237-241 (1989)
Regulation of glycogen synthase kinase-3 in human skeletal muscle: effects of food intake and bicycle exercise
Wojtaszewski, J. F., et al
Diabetes, 50, 265-269 (2001)
M Pap et al.
The Journal of biological chemistry, 273(32), 19929-19932 (1998-08-01)
Growth factor-dependent survival of a variety of mammalian cells is dependent on the activation of phosphatidylinositol (PI) 3-kinase and its downstream effector, the protein kinase Akt. Glycogen synthase kinase-3 (GSK-3) has been previously identified as a physiological target of Akt
C M Moxham et al.
The Journal of biological chemistry, 271(48), 30765-30773 (1996-11-29)
Mitogen-activated protein kinases (MAPKs) represent a conserved family of Ser/Thr protein kinases with central roles in intracellular signaling. Activation of three prominent members of the MAPK family, i.e. extracellular response kinases (ERK), jun N-terminal kinase (JNK), and p38, was defined
S R Kimball et al.
The Journal of biological chemistry, 273(47), 30945-30953 (1998-11-13)
The present study was designed to investigate the mechanism through which leucine and histidine regulate translation initiation in L6 myoblasts. The results show that both amino acids stimulate initiation and coordinately regulate the activity of eukaryotic initiation factor eIF2B. The

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