07-278
Anti-phospho-LAT (Tyr191) Antibody
Upstate®, from rabbit
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Preço e disponibilidade não estão disponíveis no momento.
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
purified antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
reatividade de espécies
human, mouse
fabricante/nome comercial
Upstate®
técnica(s)
western blot: suitable
Isotipo
IgG
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
modificação pós-traducional do alvo
phosphorylation (pTyr191)
Informações sobre genes
human ... LAT(27040)
mouse ... Lat(16797)
Especificidade
LAT phosphorylated on tyrosine 191
Imunogênio
peptide (SREpYVNVSPEQQ-C) corresponding to amino acids 188-195 of human LAT and amino acids 192-203 of mouse LAT
Aplicação
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
This Anti-phospho-LAT (Tyr191) Antibody is validated for use in WB for the detection of phospho-LAT (Tyr191).
Qualidade
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells stimulated with anti-T-cell receptor monoclonal antibody, clone C305
Descrição-alvo
36kDa
Ligação
Replaces: 04-467
forma física
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography
Armazenamento e estabilidade
2 years at -20°C
Informações legais
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Certificados de análise (COA)
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Methods in molecular biology (Clifton, N.J.), 1584, 355-368 (2017-03-04)
In T lymphocytes, the immune synapse is an active zone of vesicular traffic. Directional transport of vesicular receptors and signaling molecules from or to the immune synapse has been shown to play an important role in T-cell receptor (TCR) signal
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C-terminal Src kinase (CSK) is a major negative regulator of Src family tyrosine kinases (SFKs) that play critical roles in immunoreceptor signaling. CSK is brought in contiguity to the plasma membrane-bound SFKs via binding to transmembrane adaptor PAG, also known
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The Journal of experimental medicine, 213(12), 2759-2772 (2016-11-05)
In chronic infection, T cells become hyporesponsive to antigenic stimulation to prevent immunopathology. Here, we show that TMEM16F is required to curb excessive T cell responses in chronic infection with virus. TMEM16F-deficient T cells are hyperactivated during the early phase
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