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858141C

Avanti

17:1 Lyso PS

1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-[phospho-L-serine] (sodium salt), chloroform

Sinônimo(s):

110724

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About This Item

Fórmula empírica (Notação de Hill):
C23H43NNaO9P
Número CAS:
1246298-15-6
Peso molecular:
531.55
Código UNSPSC:
51191904
NACRES:
NA.25
Preço e disponibilidade não estão disponíveis no momento.

Ensaio

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

Formulário

liquid

embalagem

pkg of 1 × 1 mL (858141C-5mg)
pkg of 1 × 4 mL (858141C-100mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 858141C

concentração

25 mg/mL (858141C-100mg)
5 mg/mL (858141C-5mg)

tipo de lipídio

phospholipids
cardiolipins

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[Na+]

InChI

1S/C23H44NO9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22(26)31-17-20(25)18-32-34(29,30)33-19-21(24)23(27)28;/h7-8,20-21,25H,2-6,9-19,24H2,1H3,(H,27,28)(H,29,30);/q;+1/p-1/b8-7-;/t20-,21+;/m1./s1

chave InChI

OALJMCAGNYARLY-XZEOLHCOSA-M

Aplicação

17:1 Lyso PS may be used as a standard in graphitized carbon black-solid phase extraction (GCB-SPE) method for lipid extraction.[1] It may also be used as an internal standard in the metabolomic analysis of cell and brain samples.[2]

Ações bioquímicas/fisiológicas

17:1 Lyso PS may serve as an odd-chained LIPIDOMIX™quantitative mass spectrometry internal standard.

Embalagem

5 mL Clear Glass Sealed Ampule (858141C-100mg)
5 mL Clear Glass Sealed Ampule (858141C-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Órgãos-alvo

Liver,Kidney, Respiratory system

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

does not flash

Ponto de fulgor (°C)

does not flash

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Certificados de análise (COA)

Lot/Batch Number

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Daisuke Ogasawara et al.
Nature chemical biology, 14(12), 1099-1108 (2018-11-14)
ABHD12 metabolizes bioactive lysophospholipids, including lysophosphatidylserine (lyso-PS). Deleterious mutations in human ABHD12 cause the neurological disease PHARC, and ABHD12-/- mice display PHARC-like phenotypes, including hearing loss, along with elevated brain lyso-PS and features of stimulated innate immune cell function. Here
Biyu Hou et al.
Life sciences, 245, 117352-117352 (2020-02-02)
The depot-specific differences in lipidome of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) reflect heterogeneity of white adipose tissue (WAT), which plays a central role in its distinct response to outside stimuli. However, the detailed lipidome of depot-specific
Michela Antonelli et al.
Analytical and bioanalytical chemistry, 412(2), 413-423 (2019-11-25)
The chemical composition of Cannabis sativa L. has been extensively investigated for several years; nevertheless, a detailed lipidome characterization is completely lacking in the literature. To achieve this goal, an extraction and enrichment procedure was developed for the characterization of
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

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