CDE-510
Diether Liposomes
16:0 Diether PC:Cholesterol (70:30 molar ratio 1mM)
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About This Item
Código UNSPSC:
12352211
NACRES:
NA.25
Nível de qualidade
composição
Phosphate buffered saline
concentração
1 mM
Impurezas
30 mol % Cholesterol
70 mol % 16:0 Diether PC
tamanho de partícula
100 nm
pH
7.4
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Descrição geral
Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. Ether lipids are a unique class of glycerophospholipids that have an alkyl chain attached to the sn-1 position by an ether bond.
Due to distinctive properties of ether lipids, liposomes made from ether lipids exhibit very unique characters and performance:
*ether bonds are more stable than ester linkages over a wide range of acidic or alkaline pH
*stability properties of the liposomes are enhanced by biopolar lipids and the saturated alkyl chains gives stability towards degradation in oxidative conditions
*the unusual stereochemistry of the glycerol backbone enhances the resistance against phopholipases
Due to their increased stability properties, ether liposomes are suitable candates for experiments that require an extended period of time as they can neither be hydrolyzed, oxidized, and can withstand higher temperatures.
Due to distinctive properties of ether lipids, liposomes made from ether lipids exhibit very unique characters and performance:
*ether bonds are more stable than ester linkages over a wide range of acidic or alkaline pH
*stability properties of the liposomes are enhanced by biopolar lipids and the saturated alkyl chains gives stability towards degradation in oxidative conditions
*the unusual stereochemistry of the glycerol backbone enhances the resistance against phopholipases
Due to their increased stability properties, ether liposomes are suitable candates for experiments that require an extended period of time as they can neither be hydrolyzed, oxidized, and can withstand higher temperatures.
Aplicação
Drug delivery
Lipid-protein interactions
Lipid-protein interactions
Armazenamento e estabilidade
Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.
Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.
Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.
Informações legais
Cellsome is a trademark of Encapsula NanoSciences
Product of Encapsula Nanosciences
Exoneração de responsabilidade
For research use only
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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