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ALD00550

Serine Hydrolase Inhibitor-17

Name: Serine Hydrolase Inhibitor-17
Brand: ALDRICH

Sinônimo(s):

tert-Butyl 4-(1H-pyrazole-1-carbonyl)-1,4-diazepane-1-carboxylate, SHI-17

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About This Item

Fórmula empírica (Notação de Hill):

C₁₄H₂₂N₄O₃

Número CAS:

1622426-20-3

Peso molecular:

294.35

Código UNSPSC:

12352200

ID de substância PubChem:

329772714

NACRES:

NA.22

forma

solid

Nível de qualidade

100

cadeia de caracteres SMILES

O=C(N1CCCN(C(OC(C)(C)C)=O)CC1)N2N=CC=C2

InChI

1S/C14H22N4O3/c1-14(2,3)21-13(20)17-8-5-7-16(10-11-17)12(19)18-9-4-6-15-18/h4,6,9H,5,7-8,10-11H2,1-3H3

chave InChI

SREDUUSCWDQNQK-UHFFFAOYSA-N

Aplicação

Serine hydrolase inhibitors are small molecule fragments that react in vitro with the serine hydrolase class of proteins. They are amenable to further modification to create novel inhibitors of this class of protein.

Pictogramas

GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P301 + P330 + P331 + P310

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Discovery libraries targeting the major enzyme classes: the serine hydrolases.

Katerina Otrubova et al.

Bioorganic & medicinal chemistry letters, 24(16), 3807-3813 (2014-07-20)

Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subset of compounds that serve

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