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911364

Sigma-Aldrich

Poly(ethylene glycol) linear dendrimer

carboxyl terminated, PEG Mn 10k, generation 4

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About This Item

Fórmula empírica (Notação de Hill):
C732H1278O414
Peso molecular:
16703.73
Código UNSPSC:
12162002
NACRES:
NA.23

forma

solid

peso molecular

PEG Mn 10k
PEG average Mn 10,000
generation 4

Nº de grupos de superfície

32

cor

white to off-white

grupo funcional

carboxylic acid

temperatura de armazenamento

−20°C

Categorias relacionadas

Descrição geral

  • Polymer architecture: PEG-core dendrimer
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

Aplicação

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolyzable linker allows for degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. This dendritic polymer is biocompatible, biodegradable, and suitable for biomedical applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, enabling use for advanced drug delivery systems or for drug targeting. The carboxylic acid-functionalized corona can be readily used for bioconjugation reactions.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al.
Progress in Polymer Science, 48, 85-110 (2015)
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

Artigos

Dendritic Polyester Scaffolds for Drug Delivery

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

New Multi-Dendrimer Platforms for Supramolecular Assembly

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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