This product is prepared from a porcine Type A gelatin.
904643
Thiol functionalized gelatin
Sinônimo(s):
Functionalized gelatin, Gelatin thiol, Gelatin-SH• Gel-SH, SH functionalized gelatin, Thiol functionalized gelatin, Thiol gelatin, Thiolated gelatin
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1 G
R$ 734,00
About This Item
Código UNSPSC:
12352105
NACRES:
NA.23
Produtos recomendados
descrição
NMR: Conforms to structure
Thiol content 150-350 μmol/g
Ensaio
150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis)
Formulário
powder
cor
white to pale yellow
temperatura de armazenamento
−20°C
Categorias relacionadas
Aplicação
Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Functionalized gelatin can be cross-linked with the formation of covalent bonds into highly crosslinked structures, such as hydrogels. Recent literature suggests that radical-mediated polymerized hydrogels may not be ideal for cell and protein encapsulation due to radical-mediated damage, hindered molecular transport, or altered cell-cell/cell-material interactions. Thiol-modified gelatin can be used to form hydrogels with multifunctional norbornene or allyl crosslinkers via thiol-ene click or Michael-addition reactions.
To improve solubility in water, heat to 40°C and stir for 10-15 minutes.
Atenção
Material should be handled under nitrogen - air/oxygen & moisture are to be avoided.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Os clientes também visualizaram
Modular Cross-Linking of Gelatin-Based Thiol?Norbornene Hydrogels for in Vitro 3D Culture of Hepatocellular Carcinoma Cells
Greene T, et al
ACS biomaterials science & engineering, 1 (12), 1314?1323-1314?1323 (2015)
Vinh X Truong et al.
Biomacromolecules, 18(3), 757-766 (2017-02-15)
Swelling of hydrogels leads to a decrease in mechanical performance coupled with complications in solute diffusion. In addition, hydrogel swelling affects patient safety in biomedical applications such as compression of tissue and fluid blockage. A conventional strategy for suppressing swelling
Gelatin hydrogels formed by orthogonal thiol?norbornene photochemistry for cell encapsulation
Munoz Z, et al.
Biomaterials Science, 2, 1063-1072 (2014)
Artigos
Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.
Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.
Protocolos
Frequently asked questions (FAQs) for KAPA SYBR® FAST One-Step qRT-PCR Kits.
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Could I ask what gelatin is used for the modification? Is it typ A or type B, and is the origin bovine or porcin?
1 answer-
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What is the expected bloom number for product 904643?
1 answer-
It is bloom 300.
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How should it be dissolved? I tried to make a 50g/L PBS solution and left it in an incubator at 40 degrees overnight, but it did not dissolve.
1 answer-
Heat the gelatin solution to at least 50 °C while stirring continuously. The gelatin should dissolve to form a slightly hazy solution with no particulates. If the issue persists, please navigate to the link https://www.sigmaaldrich.com/techservice, and click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.
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