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857777

Sigma-Aldrich

Cytochalasin B from Helminthosporium dematioideum

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About This Item

Fórmula empírica (Notação de Hill):
C29H37NO5
Número CAS:
14930-96-2
Peso molecular:
479.61
Beilstein:
1096207
Número CE:
239-000-2
Número MDL:
MFCD00077704
Código UNSPSC:
12352103
ID de substância PubChem:
329769412

Nível de qualidade

100

cadeia de caracteres SMILES

C[C@@H]1CCC[C@@H](O)\C=C\C(=O)O[C@]23[C@@H](\C=C\C1)[C@H](O)C(=C)[C@@H](C)[C@H]2[C@H](Cc4ccccc4)NC3=O

InChI

1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,31,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1

chave InChI

GBOGMAARMMDZGR-TYHYBEHESA-N

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Frases de perigo

H300 + H310 + H330,H361

Classificações de perigo

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Repr. 2

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análise (COA)

Lot/Batch Number
08271CW
03990EV
03401TV
06793PW
08145DG

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F Marco-Jiménez et al.
Cryo letters, 33(1), 24-30 (2012-03-22)
The study tested the efficacy of pre-treating mature porcine oocytes with cytochalasin B before vitrification by the open pulled straw method (OPS) in a low toxicity solution containing ice blockers. The effects of pre-treating the oocytes with 7.5 micrograms per
M A Pogorelova et al.
Ontogenez, 43(2), 94-102 (2012-06-02)
Mouse single-cell embryos exhibit robust Regulatory Volume Decrease (RVD). In what manner the very early mammalian embryo following zygote stage is appreciably altered by the anisotonic extracellular solution is, as yet, totally unclear. Little attention was paid to this direction
François Perreault et al.
The Science of the total environment, 441, 117-124 (2012-11-10)
Copper oxide nanoparticles (CuO NPs) are used for their biocide potential however they were also shown to be highly toxic to mammalian cells. Therefore, the effects of CuO NPs should be carefully investigated to determine the most sensitive processes for
A S Pivovarov et al.
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 62(2), 222-232 (2012-06-14)
Toxins that impair the function of actin microfilaments in cytoskeleton, cytochalasin B (disrupts microfilaments by inhibiting actin polymerization) and phalloidin (binds polymeric F-actin, stabilizing it and interfering with the function of actin-rich structures) reduce the depression of acetylcholine-induced inward current
C Milligan et al.
The Journal of physiology, 591(6), 1463-1474 (2013-01-09)
Abstract  Red blood cells (RBCs) from patients with sickle cell disease (SCD) lyse in deoxygenated isosmotic non-electrolyte solutions. Haemolysis has features which suggest that it is linked to activation of the pathway termed Psickle. This pathway is usually described as
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