47296
o-Fluoro-L-phenylalanine
puriss., ≥99.0% (sum of enantiomers, HPLC)
Sinônimo(s):
2-Fluoro-L-phenylalanine
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About This Item
grau
puriss.
Ensaio
≥99.0% (sum of enantiomers, HPLC)
atividade óptica
[α]20/D −14±1°, c = 1% in H2O
pureza óptica
enantiomeric ratio: ≥99.5:0.5 (TLC)
cadeia de caracteres SMILES
N[C@@H](Cc1ccccc1F)C(O)=O
Embalagem
Bottomless glass bottle. Contents are inside inserted fused cone.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Organic & biomolecular chemistry, 9(3), 765-769 (2010-11-23)
2-[(18)F]Fluoro-L-phenylalanine and 2-[(18)F]fluoro-L-tyrosine have been developed as promising radiopharmaceuticals for molecular imaging using positron emission tomography (PET). However, the lack of a convenient radiosynthetic pathway has limited their practical use. In this work a new three-step nucleophilic synthesis of these
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 37(2), 320-325 (1996-02-01)
L-[methyl-11C]methionine (11C-Met) is a useful tracer for tumor imaging with PET. The drawbacks include a short half-life and high physiological accumulation in abdominal organs. To overcome these shortfalls, the feasible use of [18F]fluorophenylalanine (18F-Phe), which shares the same amino acid
Biochemistry, 44(17), 6675-6684 (2005-04-27)
The ribosome-catalyzed peptidyl transferase reaction displays a complex pH profile resulting from two functional groups whose deprotonation is important for the reaction, one within the A-site substrate and a second unidentified group thought to reside in the rRNA peptidyl transferase
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 36(7), 1232-1237 (1995-07-01)
Neutral amino acids (NAAs) are transported from the blood to the brain using the same carrier system in a competitive fashion. The purpose of this study is to establish a method for evaluating neutral amino acid transport at the blood-brain
Nuclear medicine and biology, 21(7), 959-962 (1994-10-01)
The anabolism of isotopically labeled amino acids was compared between the cerebrum and the cerebellum in conscious rat at three feeding conditions. After L-[2-18F]fluorophenylalanine and L-[2,6-3H]phenylalanine injections, the incorporation rate of both radioactivity into protein fraction showed no difference between
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