Pular para o conteúdo
Merck
Todas as fotos(2)

Documentos Principais

Visualizar Toda a Documentação

207713

Sigma-Aldrich

1,3-Di-o-tolylguanidine

99%

Sinônimo(s):

DTG

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(2)

About This Item

Fórmula linear:
(CH3C6H4NH)2C(=NH)
Número CAS:
97-39-2
Peso molecular:
239.32
Número CE:
202-577-6
Número MDL:
MFCD00008513
Código UNSPSC:
12352100
ID de substância PubChem:
24852467
NACRES:
NA.22
Preço e disponibilidade não estão disponíveis no momento.

Ensaio

99%

Formulário

solid

pf

176-178 °C (lit.)

solubilidade

water: soluble 70 mg/mL at 20 °C

grupo funcional

amine

cadeia de caracteres SMILES

Cc1ccccc1NC(=N)Nc2ccccc2C

InChI

1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)

chave InChI

OPNUROKCUBTKLF-UHFFFAOYSA-N

Informações sobre genes

human ... EBP(10682)

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

1,3-Di-o-tolylguanidine is a selective σ-receptor agonist[1]. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice[2].

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCW7506
MKCV7802
MKCW1600
MKCW1599
MKCW8211

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Thibault Mesplède et al.
AIDS (London, England), 29(6), 659-665 (2015-04-08)
In treatment-naive HIV-positive individuals, the integrase strand-transfer inhibitor dolutegravir (DTG) has not been associated with emergent drug-resistance mutations, neither against this drug nor against other antiretroviral drugs that were used in combination with it. This is in contrast to all
F P Monnet et al.
The Journal of pharmacology and experimental therapeutics, 307(2), 705-712 (2003-09-17)
Intracellular calcium concentration ([Ca2+]i) plays a major role in neuronal excitability, especially that triggered by the N-methyl-d-aspartate (NMDA)-sensitive glutamatergic receptor. We have previously shown that sigma1 receptor agonists potentiate NMDA receptor-mediated neuronal activity in the hippocampus and recruit Ca2+-dependent second
Zur Mira Azizah Nor Haiza Lah et al.
Journal of pharmaceutical and biomedical analysis, 174, 608-617 (2019-07-03)
A facile electrochemical sandwich immunosensor for the detection of a breast cancer biomarker, the human epidermal growth factor receptor 2 (HER2), was designed, using lead sulfide quantum dots-conjugated secondary HER2 antibody (Ab2-PbS QDs) as a label. Using Ab2-PbS QDs in
Mona Ebadi et al.
Scientific reports, 10(1), 21521-21521 (2020-12-11)
The use of nanocarriers composed of polyethylene glycol- and polyvinyl alcohol-coated vesicles encapsulating active molecules in place of conventional chemotherapy drugs can reduce many of the chemotherapy-associated challenges because of the increased drug concentration at the diseased area in the
Moya A Hay et al.
Chemical science, 10(25), 6354-6361 (2019-07-26)
The magnetic properties of 3d monometallic complexes can be tuned through geometric control, owing to their synthetic accessibility and relative structural simplicity. Monodentate ligands offer great potential for fine-tuning the coordination environment to engineer both the axial and rhombic zero-field
Exibir todos os documentos relacionados

Questions

1–3 of 3 Questions  

  1. What is the nature of the biological activity of Product 207713, 1,3-di-o-tolylguanidine?

    1 answer

    1. 1,3-Di-o-tolylguanidine is known to be a selective ligand for the sigma site in the mammalian central nervous system. Behavioral changes, such as hypothermia, reduced pain behavior, circling behavior, and decreased locomotor activity in mice and/or rats were observed after intraperitoneal, subcutaneous, intravenous and/or intranigral injection.

      Helpful?

  2. What is the solubility of Product 207713, 1,3-di-o-tolylguanidine?

    1 answer

    1. 1,3-Di-o-tolylguanidine is soluble in water at 70 micrograms per mL at ambient temperature.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

Reviews

No rating value

Active Filters

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica