194905

12-Crown-4

98%

• Sinônimo(s): 1,4,7,10-Tetraoxacyclododecane
• Fórmula empírica (Notação de Hill): C₈H₁₆O₄
• Número CAS: 294-93-9
• Peso molecular: 176.21
• Beilstein: 1363064
• Número CE: 206-036-5
• Número MDL: MFCD00005103
• Código UNSPSC: 12352005
• ID de substância PubChem: 24851661
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 98%
• Formulário: liquid
• índice de refração: n20/D 1.463 (lit.)
• p.e.: 61-70 °C/0.5 mmHg (lit.)
• pf: 16 °C (lit.)
• densidade: 1.089 g/mL at 25 °C (lit.)
• grupo funcional: ether
• cadeia de caracteres SMILES: C1COCCOCCOCCO1
• InChI: 1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2
• chave InChI: XQQZRZQVBFHBHL-UHFFFAOYSA-N

Descrição

Descrição geral

12-Crown-4 is a crown ether generally used as a ligand in coordination chemistry. It is also known as lithium ionophore because of its strong chelating property specific to lithium cation.[1][2][3]

Aplicação

12-Crown-4 can be used as:

• A promoter in the synthesis of poly(diethylsiloxane) (PDES) from monomer hexaethylcyclotrisiloxane using NaOH as a catalyst via anionic ring-opening polymerization.[4]
• As an additive in the preparation of triarylmethane derivatives by palladium-catalyzed cross coupling reaction of aryl bromides with diarylmethane derivatives.[5]
• A phase transfer catalyst in organic synthesis.[6]

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H330
• Declarações de precaução: P260 - P271 - P284 - P304 + P340 + P310 - P403 + P233 - P405
• Classificações de perigo: Acute Tox. 1 Inhalation
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 235.4 °F - closed cup
• Ponto de fulgor (°C): 113 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter