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146064

Sigma-Aldrich

β-Alanine

99%, suitable for ligand binding assays

Sinônimo(s):

β-Ala, 3-Aminopropionic acid

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About This Item

Fórmula linear:
NH2CH2CH2COOH
Número CAS:
107-95-9
Peso molecular:
89.09
Beilstein:
906793
Número CE:
203-536-5
Número MDL:
MFCD00008200
Código UNSPSC:
12352209
eCl@ss:
39030936
ID de substância PubChem:
24848760
NACRES:
NA.26

product name

β-Alanine, 99%

Ensaio

99%

forma

powder, crystals or granules

técnica(s)

ligand binding assay: suitable

cor

white

pf

202 °C (dec.) (lit.)

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

chave InChI

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Categorias relacionadas

Aplicação

β-Alanine has been used as a ligand for the orphan MAS-related receptor. It has also been used in culture media used for certain strains of yeast to test for β-alanine auxotrophy.

Ações bioquímicas/fisiológicas

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Sigma-Aldrich

A3041

β-Alanine t-butyl ester hydrochloride

7-Aminoheptanoic acid 98%

Sigma-Aldrich

284637

7-Aminoheptanoic acid

Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine.
White WH
The Journal of Biological Chemistry, 276(14), 10794-10800 (2001)
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), a-, and ?-melanocyte stimulating hormone (a-MSH, and ?-MSH), and the conserved core motif HFRW.
N?hr AC, et al.
Neurochemistry International, 102, 105-113 (2017)
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
K M Gibson et al.
Journal of neurochemistry, 81(1), 71-79 (2002-06-18)
Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated gamma-hydroxybutyrate (GHB) and total GABA in urine and total brain and liver extracts. In this study, we extend our metabolic characterization of these mutant mice by documenting
Julie Y Culbertson et al.
Nutrients, 2(1), 75-98 (2010-01-01)
Muscle carnosine has been reported to serve as a physiological buffer, possess antioxidant properties, influence enzyme regulation, and affect sarcoplasmic reticulum calcium regulation. Beta-alanine (β-ALA) is a non-essential amino acid. β-ALA supplementation (e.g., 2-6 grams/day) has been shown to increase
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