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144630

Sigma-Aldrich

α-Cyano-3-hydroxycinnamic acid

98%

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About This Item

Fórmula linear:
HOC6H4CH=C(CN)CO2H
Número CAS:
54673-07-3
Peso molecular:
189.17
Número CE:
259-289-9
Número MDL:
MFCD00004203
Código UNSPSC:
12352100
ID de substância PubChem:
24848676

Ensaio

98%

pf

232 °C (dec.) (lit.)

cadeia de caracteres SMILES

OC(=O)\C(=C\c1cccc(O)c1)C#N

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
08629MH
07816ML
08720MN

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Y H Kang et al.
Molecular and cellular biochemistry, 216(1-2), 37-46 (2001-02-24)
In the hydrogen peroxide (H2O2) apoptosis model of the murine thymocyte, redox reactant and antioxidant pyruvate prevents programmed cell death. We tested the hypothesis that such protection was mediated, at least in part, via pyruvate handling by mitochondrial metabolism. Cultured
M Wittner et al.
Pflugers Archiv : European journal of physiology, 402(1), 52-62 (1984-09-01)
Isolated segments of cortical thick ascending limbs (cTAL) of rabbit kidney were perfused in vitro and the equivalent short circuit current (Isc) was measured. In a first series all substrates were removed on either side. Isc fell rapidly to 50
N Vanderheyden et al.
The Biochemical journal, 346 Pt 1, 53-62 (2000-02-05)
Regulation of intracellular pH (pH(i)) and H(+) efflux were investigated in Trypanosoma brucei bloodstream and procyclic trypomastigotes using the fluorescent dyes 2', 7'-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein (BCECF) acetoxymethyl ester and free BCECF respectively. pH(i) in bloodstream and procyclic trypomastigotes was 7.47+/-0.06 and 7.
R B Hamat et al.
Metabolism: clinical and experimental, 31(6), 548-552 (1982-06-01)
An "in vitro" model of one type of lactic acidosis was produced in rat hemi-diaphragms with inhibitors of pyruvate oxidation. In order to obtain this inhibition in the absence of hypoxia, two actions were sought; inhibiting the mitochondrial pyruvate transporter
E Bassenge et al.
American journal of physiology. Heart and circulatory physiology, 279(5), H2431-H2438 (2000-10-25)
Myocardial ischemia-reperfusion is associated with bursts of reactive oxygen species (ROS) such as superoxide radicals (O(2)(-).). Membrane-associated NADH oxidase (NADHox) activity is a hypothetical source of O(2)(-)., implying the NADH concentration-to-NAD(+) concentration ratio ([NADH]/[NAD(+)]) as a determinant of ROS. To
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