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Merck

TRPV4

transient receptor potential cation channel, subfamily V, member 4

Sinônimos:
CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC
Espécies:
ID UniProtKB:
ID do gene:
  • Human(59341) Summary: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • Mouse(63873) transient receptor potential cation channel, subfamily V, member 4
  • Rat(66026) transient receptor potential cation channel, subfamily V, member 4
  • naked mole-rat(101706710) transient receptor potential cation channel, subfamily V, member 4
  • domestic guinea pig(100724607) transient receptor potential cation channel, subfamily V, member 4
  • sheep(101113534) transient receptor potential cation channel, subfamily V, member 4
  • domestic cat(101084907) transient receptor potential cation channel, subfamily V, member 4
  • Horse(100066552) transient receptor potential cation channel, subfamily V, member 4
  • cow(540259) transient receptor potential cation channel, subfamily V, member 4
  • chicken(395427) transient receptor potential cation channel, subfamily V, member 4
  • dog(486308) transient receptor potential cation channel, subfamily V, member 4
  • Zebrafish(557850) transient receptor potential cation channel, subfamily V, member 4

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Capsazepine, ≥98% (HPLC), solid,
Espécies
human, rat
Capsaicin, ≥95%, from Capsicum sp.,
Espécies
rat, human
Capsaicin, natural,
Espécies
rat, human
Capsaicin, from Capsicum sp., ≥50% (HPLC),
Espécies
rat, human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Espécies
human, rat, mouse

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Trpv4 Antibody, clone 1B2.6, clone 1B2.6, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
western blot
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
rat
Aplicação
western blot
Anti-TRPV4 Antibody, clone 1G10-L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
canine, human, mouse, rat
Aplicação
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-TRPV4 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, rabbit
Aplicação
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Capsaicin, ≥95%, from Capsicum sp.,
Espécies
rat, human
Capsaicin, natural,
Espécies
rat, human
Capsaicin, from Capsicum sp., ≥50% (HPLC),
Espécies
rat, human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Espécies
human, rat, mouse

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
Capsazepine, ≥98% (HPLC), solid,
Espécies
human, rat

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human TRPV4,
Espécies
human
MISSION® esiRNA, targeting mouse Trpv4,
Espécies
mouse