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Merck

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Sinônimos:
EAAT2, GLT-1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Espécies
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Espécies
rat, human
(±)-AMPA, solid,
Espécies
rat
(Aminomethyl)phosphonic acid, 99%,
Espécies
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espécies
rat, human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo anti-transportador de glutamato, Glial, serum, Chemicon®,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
Anti-Excitatory amino acid transporter 2 Antibody, clone G6, clone G6, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-Excitatory Amino Acid Transporter (GLT-1) Rabbit pAb, liquid, Calbiochem®,
Reatividade de espécies
rat
Aplicação

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Dihydrokainic acid, ≥98% (HPLC), powder,
Espécies
rat, human
(Aminomethyl)phosphonic acid, 99%,
Espécies
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espécies
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espécies
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espécies
rat, human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human SLC1A2,
Espécies
human