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Merck

PDGFB

platelet-derived growth factor beta polypeptide

Sinônimos:
PDGF-2, PDGF2, SIS, SSV, c-sis
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5155) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
  • Mouse(18591) platelet derived growth factor, B polypeptide
  • Rat(24628) platelet-derived growth factor beta polypeptide
  • naked mole-rat(101698830) platelet-derived growth factor beta polypeptide
  • dog(442986) platelet-derived growth factor beta polypeptide
  • sheep(443545) platelet-derived growth factor beta polypeptide
  • domestic guinea pig(100731469) platelet-derived growth factor beta polypeptide
  • cow(540106) platelet-derived growth factor beta polypeptide
  • chicken(374128) platelet-derived growth factor beta polypeptide
  • Zebrafish(565324) platelet derived growth factor, B polypeptide

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ELISA

Número do produto
Descrição
Espécies
Human PDGF-BB ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espécies
human
Human PDGF-BB ELISA Kit, for cell and tissue lysates,
Espécies
human
Porcine PDGFB / Platelet-derived Growth Factor Subunit B ELISA Kit, ,
Espécies
Canine PDGFB / Platelet-derived Growth Factor Subunit B ELISA Kit, ,
Espécies
dog
Rhesus Macaque PDGF-BB ELISA, for serum, plasma and cell culture supernatants,
Espécies

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PDGFB antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
Anti-Platelet-Derived Growth Factor-BB antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
human
Aplicação
neutralization
western blot
Anti-PDGF-BB Antibody, from rabbit, purified by affinity chromatography,
Reatividade de espécies
human
Aplicação
ELISA
neutralization

western blot
Anti-PDGFB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-PDGF-BB Antibody, clone 6A9.9.11, ,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot

Proteins

Número do produto
Descrição
Espécies
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espécies
human
Platelet-Derived Growth Factor from porcine platelets, PDGF, lyophilized powder, suitable for cell culture,
Espécies
PDGF-BB, recombinant human, The Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle & connective tissue.,
Espécies
human
PDGF-BB human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espécies
human
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PDGFB,
Espécies
human