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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Sinônimos:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-PDE1A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-PDE1A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Espécies
human
Vinpocetine, ≥98%, solid,
Espécies
human
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
Dipyridamole for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PDE1A,
Espécies
human
MISSION® esiRNA, targeting mouse Pde1a,
Espécies
mouse