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Merck

MTNR1A

melatonin receptor 1A

Sinônimos:
MEL-1A-R, MT1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
6-Hydroxymelatonin, ,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Luzindole, ≥90%,
Espécies
human
Melatonina, powder, ≥98% (TLC),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot

Small Molecule - Ligand

Número do produto
Descrição
Espécies
Melatonina, powder, ≥98% (TLC),
Espécies
human

Small Molecule - Precursor

Número do produto
Descrição
Espécies
N-Acetyl-5-hydroxytryptamine, ≥99% (HPLC), powder,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human MTNR1A,
Espécies
human