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Merck

MAP2K6

mitogen-activated protein kinase kinase 6

Sinônimos:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(26399) mitogen-activated protein kinase kinase 6
  • Rat(114495) mitogen-activated protein kinase kinase 6
  • dog(480454) mitogen-activated protein kinase kinase 6
  • chicken(417445) mitogen-activated protein kinase kinase 6
  • Zebrafish(65239) mitogen-activated protein kinase kinase 6
  • domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
  • naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
  • sheep(101115047) mitogen-activated protein kinase kinase 6
  • Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
  • cow(286883) mitogen-activated protein kinase kinase 6
  • domestic cat(101089813) mitogen-activated protein kinase kinase 6
  • Horse(100053056) mitogen-activated protein kinase kinase 6

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
SAPK Pathway Explorer Antibody Minipack, Upstate®,
Reatividade de espécies
Aplicação
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
PD 98,059, solid,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Espécies
human
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
Espécies
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human MAP2K6,
Espécies
human
MISSION® esiRNA, targeting mouse Map2k6,
Espécies
mouse