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Merck

JAM3

junctional adhesion molecule 3

Sinônimos:
JAM-2, JAM-3, JAM-C, JAMC
Espécies:
ID UniProtKB:
ID do gene:
  • Human(83700) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(83964) junction adhesion molecule 3
  • Rat(315509) junctional adhesion molecule 3
  • naked mole-rat(101707307) junctional adhesion molecule 3
  • domestic guinea pig(100735476) junctional adhesion molecule 3
  • sheep(101117375) junctional adhesion molecule 3
  • domestic cat(101097016) junctional adhesion molecule 3
  • cow(513412) junctional adhesion molecule 3
  • dog(489271) junctional adhesion molecule 3
  • chicken(419736) junctional adhesion molecule 3

Custom & Knockdown Gene Products

ELISA

Número do produto
Descrição
Espécies
Human JAM-C ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-JAM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-JAM3 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
guinea pig, human, mouse
Aplicação
western blot
Anti-JAM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
Monoclonal Anti-JAM3 antibody produced in mouse, clone 1D3, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human JAM3,
Espécies
human