ITCH
itchy E3 ubiquitin protein ligase
Sinônimos:
AIF4, AIP4, NAPP1, dJ468O1.1
Espécies:
Human ITCH (83737), Mouse Itch (16396), Rat Itch (311567), chicken ITCH (419145), Zebrafish itch (100331274), cow ITCH (508431), dog ITCH (477199), domestic guinea pig Itch (100724288), Horse ITCH (100069340), domestic cat ITCH (101086133) ...Mais
ID UniProtKB:
ID do gene:
- Human(83737) Summary: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
- Mouse(16396) itchy, E3 ubiquitin protein ligase
- Rat(311567) itchy E3 ubiquitin protein ligase
- chicken(419145) itchy E3 ubiquitin protein ligase
- Zebrafish(100331274) itchy E3 ubiquitin protein ligase homolog (mouse)
- cow(508431) itchy E3 ubiquitin protein ligase homolog (mouse)
- dog(477199) itchy E3 ubiquitin protein ligase
- domestic guinea pig(100724288) itchy E3 ubiquitin protein ligase
- Horse(100069340) itchy E3 ubiquitin protein ligase
- domestic cat(101086133) itchy E3 ubiquitin protein ligase
- sheep(101118041) itchy E3 ubiquitin protein ligase
- naked mole-rat(101711522) itchy E3 ubiquitin protein ligase
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti ITCH Antibody, clone 23GB6255, Rabbit Monoclonal, clone 23GB6255, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reatividade de espécies
human, rat
Aplicação
flow cytometry
western blot
western blot
Anti-phospho-ITCH (pT222) Antibody, Chemicon®, from rabbit,
Reatividade de espécies
human
Aplicação
dot blot
western blot
western blot
Anti-ITCH antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, monkey
Aplicação
western blot
Anti-ITCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti- ITCH antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot