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Merck

IDO1

indoleamine 2,3-dioxygenase 1

Sinônimos:
IDO, IDO-1, INDO
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3620) Summary: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
  • Mouse(15930) indoleamine 2,3-dioxygenase 1
  • Rat(66029) indoleamine 2,3-dioxygenase 1
  • Zebrafish(571967) indoleamine 2,3-dioxygenase 1
  • dog(475574) indoleamine 2,3-dioxygenase 1
  • domestic guinea pig(100728309) indoleamine 2,3-dioxygenase 1
  • naked mole-rat(101723745) indoleamine 2,3-dioxygenase 1
  • domestic cat(101096977) indoleamine 2,3-dioxygenase 1
  • cow(506281) indoleamine 2,3-dioxygenase 1
  • sheep(100196903) indoleamine 2,3-dioxygenase 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-IDO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-IDO1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-IDO-1 Antibody, clone 4B7 | MABF850, clone 4B7, from mouse,
Reatividade de espécies
mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-Indoleamine 2,3-dioxygenase Antibody, clone 10.1, clone 10.1, Chemicon®, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-Ido1, clone 8G11 Antibody, clone 8G11, from mouse,
Reatividade de espécies
mouse
Aplicação
flow cytometry
western blot

Proteins

Número do produto
Descrição
Espécies
Mouse IDO1, His-Tag, recombinant, expressed in E. coli,
Espécies
mouse