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Merck

GPX1

glutathione peroxidase 1

Sinônimos:
GPXD, GSHPX1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(2876) Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14775) glutathione peroxidase 1
  • Rat(24404) glutathione peroxidase 1
  • chicken(100857115) glutathione peroxidase 1
  • Thale Cress(817046) phospholipid hydroperoxide glutathione peroxidase 1
  • domestic cat(101083751) glutathione peroxidase 1
  • Domestic Rabbit(100009258) glutathione peroxidase 1
  • Horse(100053396) glutathione peroxidase 1
  • naked mole-rat(101710466) glutathione peroxidase 1
  • sheep(100820742) glutathione peroxidase 1
  • dog(442961) glutathione peroxidase 1
  • domestic guinea pig(100729115) glutathione peroxidase 1
  • cow(281209) glutathione peroxidase 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
ANTI-FLAG® M2-Peroxidase (HRP) monoclonal, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Reatividade de espécies
all
Aplicação
ELISA
Anti-GPX1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
alligator, human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-Glutathione peroxidase 1 (ISO1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, pig
Aplicação
ELISA
immunohistochemistry

western blot
ANTI-GPX1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-GPX1 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

Proteins

Número do produto
Descrição
Espécies
GPX1 human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human GPX1,
Espécies
human