Pular para o conteúdo
Merck

DIABLO

diablo, IAP-binding mitochondrial protein

Sinônimos:
DFNA64, SMAC
Espécies:
Human DIABLO (56616), Mouse Diablo (66593), Rat Diablo (288753), chicken DIABLO (416860), cow DIABLO (493999), domestic guinea pig Diablo (100724526), naked mole-rat Diablo (101708166), sheep DIABLO (101121971), dog DIABLO (477463)
ID UniProtKB:
Q9NR28, B2RDQ0, Q6W3F3, Q96LV0, Q9BT11, Q9HAV6
ID do gene:
  • Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Mouse(66593) diablo homolog (Drosophila)
  • Rat(288753) diablo, IAP-binding mitochondrial protein
  • chicken(416860) diablo, IAP-binding mitochondrial protein
  • cow(493999) diablo, IAP-binding mitochondrial protein
  • domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
  • naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
  • sheep(101121971) diablo, IAP-binding mitochondrial protein
  • dog(477463) diablo, IAP-binding mitochondrial protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Número do produto
Descrição
Espécies
RAB0841
Mouse Diablo / Diablo Homolog, Mitochondrial ELISA Kit, ,
Espécies
mouse
RAB0912
Rat DIABLO / Diablo Homolog (Drosophila) ELISA Kit, ,
Espécies
rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
PRS2411
Anti-SMAC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5701661
Anti-Smac/Diablo antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
ZRB2891
Anti-Smac/DIABLO Antibody, clone 2B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
flow cytometry
immunocytochemistry
western blot
HPA001825
Anti-DIABLO antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
SAB3500327
Anti-Smac antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

Número do produto
Descrição
Espécies
EHU145751
MISSION® esiRNA, targeting human DIABLO, RP11-512M8.5,
Espécies
human
EMU067981
MISSION® esiRNA, targeting mouse Diablo,
Espécies
mouse