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Merck

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Sinônimos:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
Reatividade de espécies
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
Aplicação
western blot
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-Aromatase Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, monkey
Aplicação
affinity binding assay
immunohistochemistry

western blot

Cell Lines

Número do produto
Descrição
Espécies
CypExpress Aromatase, ,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Letrozole, ≥98% (HPLC),
Espécies
human
Exemestane, ≥98% (HPLC),
Espécies
human
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Formestane, solid,
Espécies
human
Letrozole, British Pharmacopoeia (BP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Cyp19a1,
Espécies
mouse
MISSION® esiRNA, targeting human CYP19A1,
Espécies
human