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Merck

CHRM4

cholinergic receptor, muscarinic 4

Sinônimos:
HM4, M4R
Espécies:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), domestic guinea pig Chrm4 (100714736), naked mole-rat Chrm4 (101726411), Domestic Rabbit CHRM4 (100008791), dog CHRM4 (611314), cow CHRM4 (512928), sheep CHRM4 (101114554), domestic cat CHRM4 (101088360)
ID UniProtKB:
P08173, B2RPP4, Q0VD60, Q4VBK7
ID do gene:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
P6503
Pilocarpina, ≥99% (titration), powder,
Espécies
human
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Espécies
human
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
Espécies
human
O100
Oxotremorine M, solid,
Espécies
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
B1390
Bisacodyl, analytical standard, for drug analysis,
Espécies
human
T9778
Tropicamide, solid,
Espécies
human
S1875
(−)-Scopolamine hydrobromide trihydrate, ≥98% (HPLC), powder,
Espécies
human
A0257
Atropine sulfate salt monohydrate, ≥97% (TLC), crystalline,
Espécies
human
S8502
(−)-Scopolamine methyl bromide, ≥98% (HPLC), powder,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
MAB1578
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2, clone 18C7.2, Chemicon®, from mouse,
Reatividade de espécies
monkey
Aplicação
immunohistochemistry
immunoprecipitation (IP)
western blot
ZMS1165
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
ELISA
affinity binding assay
immunocytochemistry
western blot
SAB4300824
Anti-CHRM4 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
MAB1576
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2, purified antibody, clone 17F10.2, Chemicon®,
Reatividade de espécies
monkey, mouse, rat
Aplicação
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
51330
Harmaline, ≥95%,
Espécies
human, rat

Small Molecule - Ligand

Número do produto
Descrição
Espécies
A138
Aminobenztropine, solid,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
Espécies
mouse