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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Sinônimos:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Espécies:
ID UniProtKB:
ID do gene:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

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ELISA

Número do produto
Descrição
Espécies
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-E-Cadherin Antibody, serum, Upstate®,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-Pan-Cadherin antibody, Mouse monoclonal, clone CH-19, purified from hybridoma cell culture,
Reatividade de espécies
psammomys (sand rat), bovine, canine, cat, chicken, ferret, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, snake
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-CDH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat, clone DECMA-1, purified from hybridoma cell culture,
Reatividade de espécies
dog, mouse
Aplicação
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot

Cell Lines

Número do produto
Descrição
Espécies
MCF10A CELLS CDH1 (-/-), ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Espécies
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espécies
mouse

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Cdh1,
Espécies
mouse
MISSION® esiRNA, targeting human CDH1,
Espécies
human