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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Sinônimos:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Espécies:
ID UniProtKB:
ID do gene:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

Número do produto
Descrição
Espécies
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-E-Cadherin Antibody, serum, Upstate®,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-E-Cadherin antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide Free, clone 67A4, Chemicon®, from mouse,
Reatividade de espécies
human
Aplicação
flow cytometry
immunofluorescence
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
Reatividade de espécies
canine, human
Aplicação
ELISA
immunocytochemistry

inhibition assay

western blot

Cell Lines

Número do produto
Descrição
Espécies
MCF10A CELLS CDH1 (-/-), ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Espécies
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espécies
mouse

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CDH1,
Espécies
human
MISSION® esiRNA, targeting mouse Cdh1,
Espécies
mouse