CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
Sinônimos:
CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Espécies:
Human CCR5 (1234), Mouse Ccr5 (12774), Rat Ccr5 (117029), domestic guinea pig Ccr5 (100716672), naked mole-rat Ccr5 (101723738), Horse CCR5 (100048935), cow CCR5 (497017), sheep CCR5 (101117453), domestic cat CCR5 (493769), chicken CCR5 (420695) ...Mais
ID UniProtKB:
ID do gene:
- Human(1234) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12774) chemokine (C-C motif) receptor 5
- Rat(117029) chemokine (C-C motif) receptor 5
- domestic guinea pig(100716672) chemokine (C-C motif) receptor 5
- naked mole-rat(101723738) chemokine (C-C motif) receptor 5
- Horse(100048935) chemokine (C-C motif) receptor 5
- cow(497017) chemokine (C-C motif) receptor 5
- sheep(101117453) chemokine (C-C motif) receptor 5
- domestic cat(493769) chemokine (C-C motif) receptor 5
- chicken(420695) chemokine (C-C motif) receptor 5
- dog(484789) chemokine (C-C motif) receptor 5
- Domestic Rabbit(100101579) chemokine (C-C motif) receptor 5
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Small Molecule - Antagonist
Número do produto
Descrição
Espécies
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CCR5 (CD195) Antibody, clone HEK/1/85a/7a, clone HEK/1/85a/7a, from rat,
Reatividade de espécies
human
Aplicação
flow cytometry
immunocytochemistry
immunocytochemistry
Anti-CCR5 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-C-C Chemokine Receptor 5 Antibody, NT, Chemicon®, from rabbit,
Reatividade de espécies
human
Aplicação
western blot
Anti-CCR5, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
western blot
western blot
Monoclonal Anti-CD195-APC antibody produced in mouse, clone T21/8,
Reatividade de espécies
Aplicação
flow cytometry