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Merck

CCND2

cyclin D2

Sinônimos:
KIAK0002
Espécies:
ID UniProtKB:
ID do gene:
  • Human(894) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq, Oct 2008]
  • Mouse(12444) cyclin D2
  • Rat(64033) cyclin D2
  • domestic guinea pig(100730596) cyclin D2
  • naked mole-rat(101721480) cyclin D2
  • chicken(374047) cyclin D2
  • dog(611782) cyclin D2
  • cow(615414) cyclin D2
  • domestic cat(101090950) cyclin D2
  • sheep(100147799) cyclin D2

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-CCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-Cyclin D2 (Phospho-THR280), affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
Anti-CCND2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
proximity ligation assay

western blot
Anti-CCND2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CCND2,
Espécies
human
MISSION® esiRNA, targeting mouse Ccnd2,
Espécies
mouse