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Merck

CASP6

caspase 6, apoptosis-related cysteine peptidase

Sinônimos:
MCH2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12368) caspase 6
  • Rat(83584) caspase 6
  • dog(487899) caspase 6, apoptosis-related cysteine peptidase
  • Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
  • chicken(395477) caspase 6, apoptosis-related cysteine peptidase
  • naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
  • domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
  • cow(538409) caspase 6, apoptosis-related cysteine peptidase
  • sheep(101119820) caspase 6, apoptosis-related cysteine peptidase
  • domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
ANTI-PHOSPHO-CASPASE 6(S257) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-CASP6 (Cleaved-Asp162) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-Caspase 6 (pSer257) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
N-Acetyl-Val-Glu-Ile-Asp-al, ~99% (HPLC), powder,
Espécies
human
Caspase Inhibitor, ,
Espécies
human
NSCI, ≥97% (HPLC), solid,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CASP6,
Espécies
human
MISSION® esiRNA, targeting mouse Casp6,
Espécies
mouse