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Merck

CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1

Sinônimos:
CACNA2, CACNL2A, CCHL2A
Espécies:
ID UniProtKB:
ID do gene:
  • Human(781) Summary: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12293) calcium channel, voltage-dependent, alpha2/delta subunit 1
  • Rat(25399) calcium channel, voltage-dependent, alpha2/delta subunit 1
  • chicken(768444) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • domestic guinea pig(100728887) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • naked mole-rat(101708369) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • cow(282608) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • sheep(101123550) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • dog(610342) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • Domestic Rabbit(100009105) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • domestic cat(101099450) calcium channel, voltage-dependent, alpha 2/delta subunit 1

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Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Felodipine, solid,
Espécies
human
Nifedipine, ≥98% (HPLC), powder,
Espécies
rat, mouse, human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CACNA2D1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-CACNA2D1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-CACNA2D1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot
Anti-CACNA2D1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Monoclonal Anti-Dihydropyridine Receptor (α2 Subunit) antibody produced in mouse, clone 20A, ascites fluid, buffered aqueous solution,
Reatividade de espécies
guinea pig, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Isradipine, ≥98% (HPLC), solid,
Espécies
human
Felodipine, solid,
Espécies
human
Nifedipine, ≥98% (HPLC), powder,
Espécies
rat, mouse, human
Bepridil hydrochloride, powder,
Espécies
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Cacna2d1,
Espécies
mouse
MISSION® esiRNA, targeting human CACNA2D1,
Espécies
human
MISSION® esiRNA, targeting mouse Cacna2d1,
Espécies
mouse