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Merck

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

Sinônimos:
CACNA1HB, Cav3.2, ECA6, EIG6
Espécies:
ID UniProtKB:
ID do gene:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Calcium Channel CaV3.2 (α1H) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
rat
Aplicação
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-Cav3.2 Antibody, Chemicon®, from rabbit,
Reatividade de espécies
rat
Aplicação
western blot
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Trimethadione, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Kurtoxin, ,
Espécies
rat, mouse, human
Bepridil hydrochloride, powder,
Espécies
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Espécies
human