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Merck

CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

Sinônimos:
BIII, CACNL1A5, CACNN, Cav2.2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(774) Summary: The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(12287) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Rat(257648) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • cow(282410) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • chicken(374169) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • dog(480660) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Domestic Rabbit(100008979) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • naked mole-rat(101697609) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic guinea pig(100735203) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic cat(101087362) calcium channel, voltage-dependent, N type, alpha 1B subunit

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Cav2.2 Antibody, Chemicon®, from rabbit,
Reatividade de espécies
rat
Aplicação
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
mouse, rat
Aplicação
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Bepridil hydrochloride, powder,
Espécies
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Cacna1b,
Espécies
mouse
MISSION® esiRNA, targeting human CACNA1B,
Espécies
human