Pular para o conteúdo
Merck

ATP1A3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

Sinônimos:
AHC2, DYT12, RDP
Espécies:
ID UniProtKB:
ID do gene:
  • Human(478) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(232975) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Rat(24213) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic cat(101083636) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Horse(100069796) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • dog(612463) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • chicken(396467) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • naked mole-rat(101721146) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • cow(282598) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • sheep(101103751) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic guinea pig(100712985) ATPase, Na+/K+ transporting, alpha 3 polypeptide

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo antiNa+/K+ ATPase α-1, clone C464.6, clone C464.6, Upstate®, from mouse,
Reatividade de espécies
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Aplicação
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Na+/K+ ATPase β-1 Antibody, clone C464.8, clone C464.8, Upstate®, from mouse,
Reatividade de espécies
bovine, canine, human, rabbit, rat
Aplicação
immunohistochemistry
western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 488, clone C464.6, Upstate®, from mouse,
Reatividade de espécies
xenopus, canine, human, monkey, mouse, pig, rabbit, rat
Aplicação
flow cytometry
immunocytochemistry

western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 555, clone C464.6, Upstate®, from mouse,
Reatividade de espécies
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Aplicação
flow cytometry
immunofluorescence

western blot
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Digitoxin, ≥92% (HPLC), powder,
Espécies
human
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Digitoxin for LC assay, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Digoxin, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Atp1a3,
Espécies
mouse
MISSION® esiRNA, targeting human ATP1A3,
Espécies
human