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Merck

ADRB2

adrenoceptor beta 2, surface

Sinônimos:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Espécies:
ID UniProtKB:
ID do gene:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

Custom & Knockdown Gene Products

Small Molecule - Agonist

Número do produto
Descrição
Espécies
(−)-Isoproterenol hydrochloride, ,
Espécies
human
Salbutamol, ,
Espécies
human
Formoterol fumarate dihydrate, >98% (HPLC),
Espécies
human
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Salmeterol Xinafoate, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Espécies
human
Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Nadolol, analytical standard,
Espécies
human
Propranolol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Esmolol hydrochloride, ≥98% (HPLC), solid,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

western blot
Anti-β2-Adrenergic Receptor Antibody, clone 2B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Espécies
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Espécies
human
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Propafenone hydrochloride, ,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human ADRB2,
Espécies
human
MISSION® esiRNA, targeting mouse Adrb2,
Espécies
mouse