310778

3,4-Diethoxy-3-cyclobutene-1,2-dione

98%

• Synonym(s): Diethyl squarate, Squaric acid diethyl ester
• Linear Formula: (C₂H₅O)₂C₄(=O)₂
• CAS Number: 5231-87-8
• Molecular Weight: 170.16
• Beilstein: 640626
• MDL number: MFCD00001333
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858814
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.509 (lit.)
• bp: 95 °C/0.1 mmHg (lit.)
• density: 1.15 g/mL at 25 °C (lit.)
• functional group: ether
• SMILES string: CCOC1=C(OCC)C(=O)C1=O
• InChI: 1S/C8H10O4/c1-3-11-7-5(9)6(10)8(7)12-4-2/h3-4H2,1-2H3
• InChI key: DFSFLZCLKYZYRD-UHFFFAOYSA-N

Description

General description

The reaction of 3,4-diethoxy-3-cyclobutene-1,2-dione (squaric acid diethyl ester) with glycosylamines (formed by reducing oligosaccharides) was studied. The derivatives formed were linked to amino-functionalized lipids, solids or proteins.

Application

3,4-Dethoxy-3-cyclobutene-1,2-dione is used as a starting material for synthesis of furanones and quinones. It undergoes ethoxy substitution with amines and unsaturated organosilanes.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H315,H317,H319,H334,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves